Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasticity of T(reg) cells: is reprogramming of T(reg) cells possible in the presence of FOXP3?

International immunopharmacology - 1 May 2011

Beyer Marc, Schultze Joachim L

Abstract excerpt

Regulatory T cells (T(reg) cells) are involved in self tolerance, immune homeostasis, prevention of autoimmunity, and suppression of immunity to pathogens or tumors. The forkhead transcription factor FOXP3 is essential for T(reg)-cell development and function as mutations in FOXP3 cause severe autoimmune diseases in mice and humans. Over the last years it has been postulated that FOXP3 expression in T(reg)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases
Share to Cell Differentiation
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Transcription Factors

Share to Gene Expression Regulation

Share to Immunologic Memory

Share to T-Lymphocyte Subsets

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 21115121
DOI: 10.1016/j.intimp.2010.11.024

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasticity of T(reg) cells: is reprogramming of T(reg) cells possible in the presence of FOXP3?PMID 21115121Read ↗

FOXP3 modifies the phenotypic and functional properties of regulatory T cells.Semantic proximity Read ↗

Regulatory T cells and Foxp3.Semantic proximity Read ↗

Regulatory T Cells in Autoimmunity and Cancer: A Duplicitous Lifestyle.Semantic proximity Read ↗

Forkhead box P3: the peacekeeper of the immune system.Semantic proximity Read ↗

Regulatory T-cells: diverse phenotypes integral to immune homeostasis and suppression.Semantic proximity Read ↗

Lineage stability and phenotypic plasticity of Foxp3⁺ regulatory T cells.Semantic proximity Read ↗

Control of regulatory T cell development by the transcription factor Foxp3.Semantic proximity Read ↗

Regulatory T cells in human autoimmune diseases.Semantic proximity Read ↗

FOXP3 Mutations and Instability as Determinants of Regulatory T-Cell Plasticity in Endocrine Autoimmunity.Semantic proximity Read ↗

CD8+ Foxp3+ T cells share developmental and phenotypic features with classical CD4+ Foxp3+ regulatory T cells but lack potent suppressive activity.Semantic proximity Read ↗

CD4⁺ T cells from IPEX patients convert into functional and stable regulatory T cells by FOXP3 gene transfer.Semantic proximity Read ↗

Human T regulatory cells: on the way to cognition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.