Article
Macrophage migration inhibitory factor gene polymorphisms (SNP -173 G>C and STR-794 CATT5-8) confer risk of plaque psoriasis: A case-control study.
Journal of clinical laboratory analysis - 1 Nov 2021
Hernández-Bello Jorge, Rodríguez-Puente Miroslaba, Gutiérrez-Cuevas Jorge, García-Arellano Samuel, Muñoz-Valle José Francisco, Fafutis-Morris Mary, Villanueva-Quintero Delfina Guadalupe, Alvarado-Navarro Anabell
Abstract excerpt
BACKGROUND: Macrophage inhibitory factor (MIF) is a pro-inflammatory cytokine secreted by several cells, including those in the immune system and the skin. The MIF gene contains the SNP -173 G> C and STR -794 CATT5-8 polymorphisms in the promoter region capable of affecting its activity. Our objective was to investigate the MIF polymorphisms as a risk factor for plaque psoriasis (PP) in the Mexican population....
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