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Article

Association between STR -794 CATT5-8 and SNP -173 G/C polymorphisms in the MIF gene and Lepromatous Leprosy in Mestizo patients of western Mexico.

Human immunology - 1 Oct 2016

Martinez-Guzman M A, Alvarado-Navarro A, Pereira-Suarez A L, Muñoz-Valle J F, Fafutis-Morris M

Abstract excerpt

Lepromatous Leprosy (LL) is the most common presentation of leprosy in Mexico. LL patients are unable to activate an effective inflammatory response against Mycobacterium leprae probably due to the genetics of the host. Macrophage Migration Inhibitory Factor (MIF) is important to trigger inflammation processes. Two polymorphisms have been reported for human MIF: STR -794 CATT5-8 and SNP -173 G/C. 7-8 CATT repeats...

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Identifiers

PMID: 27426952
DOI: 10.1016/j.humimm.2016.07.006

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MIF

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