Article
Macrophage migration inhibitory factor gene polymorphism is associated with psoriasis.
The Journal of investigative dermatology - 1 Sept 2004
Donn Rachelle P, Plant Darren, Jury Francine, Richards Helen L, Worthington Jane, Ray David W, Griffiths Christopher E M
Abstract excerpt
Macrophage migration inhibitory factor (MIF), an important pro-inflammatory cytokine, is over-expressed in plaques of psoriasis and increased levels are found in the sera of patients with psoriasis. Promoter polymorphisms of the MIF gene are associated with increased production of MIF and have been found to confer increased risk of susceptibility to chronic inflammatory diseases. We investigated whether there is...
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