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Article

Association between PON1 5'-regulatory region polymorphisms, PON1 activity and ischemic stroke.

Clinical biochemistry - 1 Jun 2009

Kim No Soo, Kang Byoung Kab, Cha Min Ho, Oh Se-Mi, Ko Mi Mi, Bang Ok-Sun

Abstract excerpt

OBJECTIVES: Paraoxonase I (PON1) was known as a risk factor for cerebrovascular diseases. This study assessed the association of single nucleotide polymorphisms (SNPs) in the PON1 5'-regulatory region with ischemic stroke and serum PON1 activity. DESIGN AND METHODS: Study subjects consisted of 418 healthy controls and 86 ischemic stroke patients with small vessel occlusion. SNPs were identified by DNA sequencing...

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Source

Identifiers

PMID: 19233151
DOI: 10.1016/j.clinbiochem.2009.02.008

Genes

PON1

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