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Article

Risk of Pancreatic Cancer Among Individuals With Pathogenic Variants in the ATM Gene

16 Sept 2021

Abstract excerpt

IMPORTANCE: Pathogenic germline variants in the ATM gene have been associated with pancreatic cancer risk. Although genetic testing identifies these variants in approximately 1% to 3% of unselected patients with pancreatic cancer, the lifetime risk of pancreatic cancer among individuals with pathogenic ATM variants has not been well estimated. OBJECTIVE: To estimate age-specific penetrance of pancreatic cancer in...

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Identifiers

PMID: 34529012
DOI: 10.1001/jamaoncol.2021.3701

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