Article
Olfactory Entry Promotes Herpesvirus Recombination.
Journal of virology - 9 Nov 2021
Xie Wanxiaojie, Bruce Kimberley, Farrell Helen E, Stevenson Philip G
Abstract excerpt
Herpesvirus genomes show abundant evidence of past recombination. Its functional importance is unknown. A key question is whether recombinant viruses can outpace the immunity induced by their parents to reach higher loads. We tested this by coinfecting mice with attenuated mutants of murid herpesvirus 4 (MuHV-4). Infection by the natural olfactory route routinely allowed mutant viruses to reconstitute wild-type...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
