Article
Viral gene drive spread during herpes simplex virus 1 infection in mice
2023-12-08
Abstract excerpt
Gene drives are genetic modifications designed to propagate efficiently through a population. Most applications rely on homologous recombination during sexual reproduction in diploid organisms such as insects, but we recently developed a gene drive in herpesviruses that relies on co-infection of cells by wild-type and engineered viruses. Here, we developed a viral gene drive against human herpes simplex virus 1 (H...
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Identifiers and source
- Literature Corpus work
- 8de84fb5-0b15-51c8-8291-f2051c534e42
- DOI
- 10.1101/2023.12.07.570711