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Article

[Clinical impact of gene mutations on myeloproliferative neoplasms in Japan].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2021

Morishita Soji

Abstract excerpt

Myeloproliferative neoplasms (MPN) are caused by somatic mutations in hematopoietic stem/progenitor cells and result in excessive increase in the blood cell mass in the peripheral blood and/or fibrosis in the bone marrow. JAK2, CALR, and MPL mutations are well-known driver mutations of MPN and are widely applied as diagnostic markers of MPN. Moreover, several studies using massive parallel sequencing technologies...

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Identifiers

PMID: 34497192
DOI: 10.11406/rinketsu.62.1060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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