Article
[Latest Research Advance of Myeloproliferative Diseases Related Genes-Review].
Zhongguo shi yan xue ye xue za zhi - 1 Aug 2017
Xiao Yu-Hong, Wang Yi-Hao, Shao Zong-Hong
Abstract excerpt
JAK2, MPL and CALR gene mutations play an important role in the onset of myeloproliferative disease(MPD). The latest researches show that the difference of ATP binding ability between the wild type JAK2 protein and mutated JAK2 protein can help us understand the pathogenesis of the MPD further, and the clinical manifestation is related to the mutation burden of the JAK2. In some ET and PMF patients, research find...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
