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[Research Progress on Gene Mutation and CHIP in Pathogenesis of MDS --Review].

Zhongguo shi yan xue ye xue za zhi - 1 Jun 2023

He Miao, Wu Tao

Abstract excerpt

With the development of molecular biology techniques, the people's understanding of myelodysplastic syndromes (MDS) has greatly improved, a heterogeneous hematopoietic pre-malignant disorder of the stem cells. Gene mutations include RNA splicing, DNA methylation, chromosome modification, transcription factors, signal transduction kinases, RAS pathways, cohesion complexes, DNA repair, etc. Gene mutation is the...

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PMID: 37356959
DOI: 10.19746/j.cnki.issn.1009-2137.2023.03.043

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