Article
[Current Understanding of Myeloproliferative Neoplasm-Related Gene Mutations and Cytokine -Review].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2018
He Zhi-Peng, Wu Yong
Abstract excerpt
Myeloproliferative neoplasm(MPN) is clonal hematopoietic stem cell disorder characterized by abnormal proliferation and expansion of one or more myeloid lineages. BCR-ABL-negative MPN includes polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF). The mutations of JAK2, CALR and MPL genes are involved in the pathogenesis of MPN that provided a more complete molecular diagnostic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
