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Article

Clinical impacts of the mutational spectrum in Japanese patients with primary myelofibrosis.

International journal of hematology - 1 Apr 2021

Morishita Soji, Ochiai Tomonori, Misawa Kyohei, Osaga Satoshi, Inano Tadaaki, Fukuda Yasutaka, Edahiro Yoko, Ohsaka Akimichi, Araki Marito, Komatsu Norio

Abstract excerpt

Patients with primary myelofibrosis (PMF) have a poorer prognosis than those with other subtypes of myeloproliferative neoplasms (MPNs). To investigate the relationship between gene mutations and the prognosis of Japanese PMF patients, we analyzed mutations in 72 regions located in 14 MPN-relevant genes (CSF3R, MPL, JAK2, CALR, DNMT3A, TET2, EZH2, ASXL1, IDH1/2, SRSF2, SF3B1, U2AF1, and TP53) utilizing a target...

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Identifiers

PMID: 33389584
DOI: 10.1007/s12185-020-03054-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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