Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Melanoma cells adopt features of both mesenchymal and amoeboid migration within confining channels.

Scientific reports - 7 Sept 2021

Gabbireddy Sairisheel R, Vosatka Karl W, Chung Aram J, Logue Jeremy S

Abstract excerpt

For metastasis to occur, cancer cells must traverse a range of tissue environments. In part, this is accomplished by cells adjusting their migration mode to one that is best suited to the environment. Melanoma cells have been shown to be particularly plastic, frequently using both mesenchymal and amoeboid (bleb-based) modes of migration. It has been demonstrated that 2D confinement will promote the transition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin-Related Protein 2-3 Complex
Share to Cell Shape

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Equipment Design

Share to Fibronectins

Share to Focal Adhesions

Share to Mesoderm

Share to Pseudopodia

Share to Stress, Mechanical

Source

Open in PubMed Open full text

Identifiers

PMID: 34493759
DOI: 10.1038/s41598-021-97348-7
PMCID: PMC8423822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Melanoma cells adopt features of both mesenchymal and amoeboid migration within confining channels.PMID 34493759Read ↗

The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and MetastasisSemantic proximity Read ↗

In vivo evidence for bleb-induced survival signaling in metastatic melanomaSemantic proximity Read ↗

A quantitative comparison of human HT-1080 fibrosarcoma cells and primary human dermal fibroblasts identifies a 3D migration mechanism with properties unique to the transformed phenotype.Semantic proximity Read ↗

Blebs Promote Cell Survival by Assembling Oncogenic Signaling HubsSemantic proximity Read ↗

Melanoma in the Eyes of MechanobiologySemantic proximity Read ↗

3D Model of the Early Melanoma Microenvironment Captures Macrophage Transition into a Tumor-Promoting PhenotypeSemantic proximity Read ↗

TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and DisseminationSemantic proximity Read ↗

Blebs promote cell survival by assembling oncogenic signalling hubs.Semantic proximity Read ↗

Modeling and predictions of biphasic mechanosensitive cell migration altered by cell-intrinsic properties and matrix confinement.Semantic proximity Read ↗

Differentiation States of Phenotypic Transition of Melanoma Cells Are Revealed by 3D Cell Cultures.Semantic proximity Read ↗

Physical view on migration modesSemantic proximity Read ↗

Distinct signaling mechanisms regulate migration in unconfined versus confined spaces.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.