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Natural Killer Cells as Key Mediators in Type I Diabetes Immunopathology

20 Aug 2021

Abstract excerpt

The immunopathology of type I diabetes (T1D) presents a complicated case in part because of the multifactorial origin of this disease. Typically, T1D is thought to occur as a result of autoimmunity toward islets of Langerhans, resulting in the destruction of insulin-producing cells (β cells) and thus lifelong reliance on exogenous insulin. However, that explanation obscures much of the underlying mechanism, and...

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PMID: 34489972
DOI: 10.3389/fimmu.2021.722979

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