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Beta cell and immune cell interactions in autoimmune type 1 diabetes: How they meet and talk to each other

6 Aug 2022

Abstract excerpt

BACKGROUND: The highly complex pathogenesis of Type 1 Diabetes is driven by several immune cell types with both effector and regulatory characteristics, which ultimately ends in the destruction of the insulin-producing beta cells. There are multiple layers of interaction between these immune cell populations and the pancreatic islets. SCOPE OF REVIEW: In this review article, we aim to discuss important recent...

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PMID: 35944899
DOI: 10.1016/j.molmet.2022.101565

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