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Article

MiR-100 overexpression attenuates high fat diet induced weight gain, liver steatosis, hypertriglyceridemia and development of metabolic syndrome in mice.

Molecular medicine (Cambridge, Mass.) - 6 Sept 2021

Smolka Christian, Schlösser Delia, Hohnloser Catherine, Bemtgen Xavier, Jänich Caterina, Schneider Laura, Martin Julien, Pfeifer Dietmar, Moser Martin, Hasselblatt Peter, Bode Christoph, Grundmann Sebastian, Pankratz Franziska

Abstract excerpt

BACKGROUND: Diet-induced obesity can result in the development of a diverse spectrum of cardiovascular and metabolic diseases, including type 2 diabetes, dyslipidemia, non-alcoholic liver steatosis and atherosclerotic disease. MicroRNAs have been described to be important regulators of metabolism and disease development. METHODS: In the current study, we investigated the effects of ubiquitous miR-100...

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Identifiers

PMID: 34488621
DOI: 10.1186/s10020-021-00364-6
PMCID: PMC8422764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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