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Article

Clinical implication and prognostic significance of FLT3-ITD and ASXL1 mutations in Egyptian AML patients: A single-center study.

Cancer biomarkers : section A of Disease markers - 1 Jan 2021

Ebian Huda F, Elshorbagy Sherin, Mohamed Haitham, Embaby Ahmad, Khamis Tarek, Sameh Reham, Sabbah Norhan A, Hussein Samia

Abstract excerpt

BACKGROUND: Both Fms-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) and Additional Sex Comb-like 1 (ASXL1) mutations are frequent and early genetic alteration events in acute myeloid leukemia (AML) patients. These genetic alterations may be associated with an unfavorable prognosis. OBJECTIVE: Up to our knowledge, this is the first study performed to evaluate the clinical implication and prognostic...

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Source

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Identifiers

PMID: 34487021
DOI: 10.3233/CBM-210024
PMCID: PMC12500060

Genes

ASXL1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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