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Article

Acquired mutations in ASXL1 in acute myeloid leukemia: prevalence and prognostic value.

Haematologica - 1 Mar 2012

Pratcorona Marta, Abbas Saman, Sanders Mathijs A, Koenders Jasper E, Kavelaars François G, Erpelinck-Verschueren Claudia A J, Zeilemakers Annelieke, Löwenberg Bob, Valk Peter J M

Abstract excerpt

Somatic mutations in the additional sex comb-like 1 (ASXL1) gene have been described in various types of myeloid malignancies, including acute myeloid leukemia. Analysis of novel markers, such as ASXL1 mutations, in independent clinical trials is indispensable before considering them for clinical decision-making. We analyzed 882 well-characterized acute myeloid leukemia cases to determine the prevalence and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22058207
DOI: 10.3324/haematol.2011.051532
PMCID: PMC3291593

Genes

ASXL1
FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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