Article
Hereditary pancreatic cancer.
International journal of clinical oncology - 1 Oct 2021
Abe Kodai, Kitago Minoru, Kitagawa Yuko, Hirasawa Akira
Abstract excerpt
Pancreatic cancer is associated with both family and hereditary cancer syndromes. Multigene panel testing for pancreatic cancer detected the germline variants BRCA1/2, PALB2, ATM, TP53, MLH1, STK11/LKB1, APC, CDKN2A, and SPINK1/PRSS1 as high-risk genes. A latest genome-wide association study revealed the common, but low-risk germline variants in pancreatic cancer patients. Active pancreatic surveillance using...
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