Article
Molecular Features and Clinical Management of Hereditary Pancreatic Cancer Syndromes and Familial Pancreatic Cancer.
International journal of molecular sciences - 21 Jan 2022
Kasuga Akiyoshi, Okamoto Takeshi, Udagawa Shohei, Mori Chinatsu, Mie Takafumi, Furukawa Takaaki, Yamada Yuto, Takeda Tsuyoshi, Matsuyama Masato, Sasaki Takashi, Ozaka Masato, Ueki Arisa, Sasahira Naoki
Abstract excerpt
Hereditary pancreatic cancers are caused by several inherited genes. Familial pancreatic cancer is defined as pancreatic cancer arising in a patient with at least two first-degree relatives with pancreatic cancer in the absence of an identified genetic cause. Hereditary pancreatic cancer syndromes and familial pancreatic cancers account for about 10% of pancreatic cancer cases. Germline mutations in BRCA1, BRCA2,...
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