Article
BRCA mutated pancreatic cancer: A change is coming.
World journal of gastroenterology - 7 May 2021
Rosen Michael N, Goodwin Rachel A, Vickers Michael M
Abstract excerpt
Pancreatic cancer remains a leading cause of cancer-related death with few available therapies for advanced disease. Recently, patients with germline BRCA mutations have received increased attention due to advances in the management of BRCA mutated ovarian and breast tumors. Germline BRCA mutations significantly increase risk of developing pancreatic cancer and can be found in up to 8% of patients with sporadic...
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