Article
Susceptibility of CTLA-4 -1661A/G polymorphism towards severity of rheumatic heart disease.
Indian heart journal - 1 Jan 2000
Bansal Ankit, Tasnim Sana, Gupta Mohit D, Mp Girish, Batra Vishal, Kohli Samantha, Tyagi Sanjay, Pasha M A Qadar
Abstract excerpt
AIM: Genetic contribution in acute rheumatic fever (ARF)/rheumatic heart disease (RHD) has been suggested but not according to severity of the valve involvement. This study attempts to identify the relevance of CTLA-4 polymorphism with severity of the disease. METHODS: In a case-control design, 291 healthy controls and 83 patients were genotyped for association between RHD and single-nucleotide...
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