Article
Transforming growth factor-beta1 gene C-509T and T869C polymorphisms as possible risk factors in rheumatic heart disease in Egypt.
Acta cardiologica - 1 Apr 2010
Kamal Hanan, Hussein Gehan, Hassoba Howayda, Mosaad Nesrin, Gad Amal, Ismail Mosleh
Abstract excerpt
OBJECTIVE: The objective of this study was to investigate the possible relationship between the TGF-beta1 gene C-509T and T869C polymorphisms and rheumatic heart disease (RHD), as well as their clinical significance. METHODS: Seventy-three patients with RHD diagnosed by echocardiography (mean age 31.7 +/- 14.7 y, male: female ratio 20:53) and, fifty-five age and sex-matched unrelated healthy volunteers (normal...
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