Article
Cytotoxic T lymphocyte-associated antigen-4 polymorphism in patients with rheumatic heart disease.
Tissue antigens - 1 Dec 2009
Düzgün N, Duman T, Haydardedeoğlu F E, Tutkak H
Abstract excerpt
Acute rheumatic fever (ARF) is a systemic inflammatory disease occurring as a consequence of an exaggerated immune response to group A, beta haemolytic streptococcal pharyngitis. The molecular mimicry between human target organs/tissues and specific components of the infectious organism leads to the development of autoimmune reactions and cardiac tissue damage in rheumatic heart disease (RHD). Cytotoxic T...
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