Article
Genetics of Parkinson's disease in Brazil: a systematic review of monogenic forms.
Arquivos de neuro-psiquiatria - 1 Jul 2021
Santos-Lobato Bruno L, Schumacher-Schuh Artur, Mata Ignacio F, Letro Grace H, Braga-Neto Pedro, Brandão Pedro R P, Godeiro-Junior Clécio O, Coletta Marcus V Della, Camargos Sarah T, Borges Vanderci, Rieder Carlos R M, Tumas Vitor
Abstract excerpt
BACKGROUND: Increasing numbers of mutations causing monogenic forms of Parkinson's disease (PD) have been described, mostly among patients in Europe and North America. Since genetic architecture varies between different populations, studying the specific genetic profile of Brazilian patients is essential for improving genetic counseling and for selecting patients for clinical trials. OBJECTIVE: We conducted a...
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