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Article

Parkinson's disease: from monogenic forms to genetic susceptibility factors.

Human molecular genetics - 15 Apr 2009

Lesage Suzanne, Brice Alexis

Abstract excerpt

Research in Parkinson's disease (PD) genetics has been extremely prolific over the past decade. More than 13 loci and 9 genes have been identified, but their implication in PD is not always certain. Point mutations, duplications and triplications in the alpha-synuclein (SNCA) gene cause a rare dominant form of PD in familial and sporadic cases. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are a more...

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Source

Identifiers

PMID: 19297401
DOI: 10.1093/hmg/ddp012

Genes

SNCA
PINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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