Article
The genetics of Parkinson disease.
Journal of geriatric psychiatry and neurology - 1 Dec 2010
Bekris Lynn M, Mata Ignacio F, Zabetian Cyrus P
Abstract excerpt
Parkinson disease (PD) is the second most common neurodegenerative disorder. In most instances, PD is thought to result from a complex interaction between multiple genetic and environmental factors, though rare monogenic forms of the disease do exist. Mutations in 6 genes (SNCA, LRRK2, PRKN, DJ1, PINK1, and ATP13A2) have conclusively been shown to cause familial parkinsonism. In addition, common variation in 3...
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