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Article

Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2.

BMC neurology - 22 Jan 2008

Bras Jose, Guerreiro Rita, Ribeiro Maria, Morgadinho Ana, Januario Cristina, Dias Margarida, Calado Ana, Semedo Cristina, Oliveira Catarina, Hardy John, Singleton Andrew

Abstract excerpt

BACKGROUND: Mutations in the genes PRKN and LRRK2 are the most frequent known genetic lesions among Parkinson's disease patients. We have previously reported that in the Portuguese population the LRRK2 c.6055G > A; p.G2019S mutation has one of the highest frequencies in Europe. METHODS: Here, we follow up on those results, screening not only LRRK2, but also PRKN, SNCA and PINK1 in a cohort of early-onset and...

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Source

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Identifiers

PMID: 18211709
DOI: 10.1186/1471-2377-8-1
PMCID: PMC2248204

Genes

PRKN
PINK1
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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