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Article

Phenotypic Characterization of the Endocannabinoid-Degrading Enzyme Alpha/Beta-Hydrolase Domain 6 Knockout Rat.

Cannabis and cannabinoid research - 1 Apr 2022

Noguchi Katsuhiko, Kadekawa Katsumi, Nishijima Saori, Sakanashi Mayuko, Okitsu-Sakurayama Shiho, Higa-Nakamine Sayomi, Yamamoto Hideyuki, Sugaya Kimio

Abstract excerpt

Introduction: Alpha/beta-hydrolase domain 6 (ABHD6) is an enzyme that hydrolyzes 2-arachidonoylglycerol, a high-efficiency endogenous cannabinoid. Although the endocannabinoid system has been suggested to be involved in regulation of bladder function, the roles of ABHD6 in the control of micturition remain unknown. To elucidate the physiological and pathological roles of ABHD6 in vivo, we examined phenotypes of...

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Identifiers

PMID: 34468198
DOI: 10.1089/can.2021.0011
PMCID: PMC9070737

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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