Signaling through Syk or CARD9 Mediates Species-Specific Anti-CandidaProtection in Bone Marrow Chimeric Mice

Abstract excerpt

While C. albicans remains the most clinically significantCandidaspecies, C. parapsilosis is an emerging pathogen with increased affinity to neonates. Syk/CARD9 signaling is crucial in immunity to C. albicans , but its role inin vivoresponses to other pathogenicCandidaspecies is largely unexplored.

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