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Article

Lack of TYK2 signaling enhances host resistance to Candida albicans skin infection

2 Dec 2024

Abstract excerpt

Candida albicans is the most common human fungal pathogen, causing diseases ranging from local to life-threating systemic infections. Tyrosine kinase 2 (TYK2), a crucial mediator in several cytokine signaling pathways, has been associated with protective functions in various microbial infections. However, its specific contribution in the immune response to fungal infections has remained elusive. In this study, we...

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PMID: 39622833
DOI: 10.1038/s41467-024-54888-6

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