Article
Genetic susceptibility to Candida infections.
EMBO molecular medicine - 1 Jun 2013
Smeekens Sanne P, van de Veerdonk Frank L, Kullberg Bart Jan, Netea Mihai G
Abstract excerpt
Candida spp. are medically important fungi causing severe mucosal and life-threatening invasive infections, especially in immunocompromised hosts. However, not all individuals at risk develop Candida infections, and it is believed that genetic variation plays an important role in host susceptibility. On the one hand, severe fungal infections are associated with monogenic primary immunodeficiencies such as defects...
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