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Article

Genetic and immune characteristics of sentinel lymph node metastases and multiple lymph node metastases compared to their matched primary breast tumours.

EBioMedicine - 1 Sept 2021

Chen Bo, Zhang Guochun, Lai Jianguo, Xiao Weikai, Li Xuerui, Li Cheukfai, Mok Hsiaopei, Li Kai, Wang Yulei, Cao Li, Jia Minghan, Ren Chongyang, Wen Lingzhu, Wei Guangnan, Lin Jiali, Li Yingzi, Zhang Yuchen, Chen Xiaoqing, Wu Xueying, Zhang Henghui, Li Min, Liu Jing, Balch Charles M, Liao Ning

Abstract excerpt

BACKGROUND: Patients with breast cancer presenting with single lymph node metastasis (from a sentinel node) experience prolonged survival compared to patients with multiple lymph node metastases (≥3). However, little information is available on the genetic and immunological characteristics of breast cancer metastases within the regional lymph nodes as they progress from the sentinel lymph node (SLN) downstream to...

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Identifiers

PMID: 34454403
DOI: 10.1016/j.ebiom.2021.103542
PMCID: PMC8399410

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