Article
Differential gene expression profiling of primary cutaneous melanoma and sentinel lymph node metastases.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2012
Koh Stephen S, Wei Jia-Perng J, Li Xinmin, Huang Rong R, Doan Ngan B, Scolyer Richard A, Cochran Alistair J, Binder Scott W
Abstract excerpt
Limited understanding of molecular mechanisms of metastasis in melanoma contributes to the absence of effective treatments. Increased knowledge of alterations in genes that underpin critical molecular events that lead to metastasis is essential. We have investigated the gene expression profiles of primary melanomas and melanoma metastases in sentinel lymph nodes. A total of 19 samples (10 primary melanomas and 9...
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