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Characterisation of a Japanese Encephalitis virus genotype 4 isolate from the 2022 Australian outbreak

10 May 2024

Abstract excerpt

Abstract Human infections with the Japanese encephalitis virus (JEV) are a leading cause of viral encephalitis. An unprecedented outbreak of JEV genotype 4 was recently reported in Australia, with an isolate (JEVNSW/22) obtained from a stillborn piglet brain. Herein we conduct a thorough characterization of JEVNSW/22 in three different mouse strains and in human cortical brain organoids (hBOs), and determined the...

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PMID: 40295675
DOI: 10.1038/s44298-024-00025-5

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