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Myeloproliferative disorders and their effects on bone homeostasis: the role of megakaryocytes

24 Aug 2021

Abstract excerpt

Myeloproliferative neoplasms (MPNs) are a heterogeneous group of chronic hematological diseases that arise from the clonal expansion of abnormal hematopoietic stem cells, of which polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) have been extensively reviewed in the context of control of clonal expansion, fibrosis, and other phenotypes. Herein, we review current knowledge on...

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PMID: 34428274
DOI: 10.1182/blood.2021011480

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