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Megakaryocytic morphology and clinical parameters in essential thrombocythemia, polycythemia vera, and primary myelofibrosis with and without JAK2 V617F.

Archives of pathology & laboratory medicine - 1 Sept 2014

Vytrva Nataliya, Stacher Elvira, Regitnig Peter, Zinke-Cerwenka Wilma, Hojas Sabine, Hubmann Eva, Porwit Anna, Bjorkholm Magnus, Hoefler Gerald, Beham-Schmid Christine

Abstract excerpt

CONTEXT: Megakaryocytes are the "hallmark" of Philadelphia chromosome-negative myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera, and primary myelofibrosis; their morphology in correlation with Janus kinase 2 (JAK2 V617F) mutation as well as clinical and laboratory parameters remains unknown. OBJECTIVE: To assess the morphology of megakaryocytes in bone marrow biopsies of patients...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 25171702
DOI: 10.5858/arpa.2013-0018-OA

Genes

JAK2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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