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Recent advances in understanding myelofibrosis and essential thrombocythemia

19 Apr 2016

Abstract excerpt

The classic BCR-ABL -negative myeloproliferative neoplasms (MPNs), a form of chronic malignant hemopathies, have been classified into polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). ET and PMF are two similar disorders in their pathogenesis, which is marked by a key role of the megakaryocyte (MK) lineage. Whereas ET is characterized by MK proliferation, PMF is also...

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PMID: 27134742
DOI: 10.12688/f1000research.8081.1

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