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Article

PADI2 Polymorphisms Are Significantly Associated With Rheumatoid Arthritis, Autoantibodies Serologic Status and Joint Damage in Women from Southern Mexico.

Frontiers in immunology - 1 Jan 2021

Guzmán-Guzmán Iris Paola, Ramírez-Vélez Claudia Isabel, Falfán-Valencia Ramcés, Navarro-Zarza José Eduardo, Gutiérrez-Pérez Ilse Adriana, Zaragoza-García Oscar, Ramírez Mónica, Castro-Alarcón Natividad, Parra-Rojas Isela

Abstract excerpt

The enzymes of the family peptidylarginine deiminases (PADs) have an important role in the pathogenesis of rheumatoid arthritis (RA) due to their association with the anti-citrullinated protein antibodies (ACPA) production. To evaluate the association between single-nucleotide polymorphisms (SNPs) in the PADI2 gene and RA susceptibility, related clinical parameters, and the serologic status of autoantibodies in a...

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Source

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Identifiers

PMID: 34421923
DOI: 10.3389/fimmu.2021.718246
PMCID: PMC8371707

Genes

PADI2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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PADI2 Polymorphisms Are Significantly Associated With Rheumatoid Arthritis, Autoantibodies Serologic Status and Joint Damage in Women from Southern Mexico.PMID 34421923Read ↗

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