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Article

Molecular Factors in PAD2 (PADI2) and PAD4 (PADI4) Are Associated with Interstitial Lung Disease Susceptibility in Rheumatoid Arthritis Patients.

Cells - 8 Sept 2023

Nava-Quiroz Karol J, Rojas-Serrano Jorge, Pérez-Rubio Gloria, Buendia-Roldan Ivette, Mejía Mayra, Fernández-López Juan Carlos, Rodríguez-Henríquez Pedro, Ayala-Alcantar Noé, Ramos-Martínez Espiridión, López-Flores Luis Alberto, Del Ángel-Pablo Alma D, Falfán-Valencia Ramcés

Abstract excerpt

Around 50% of rheumatoid arthritis (RA) patients show some extra-articular manifestation, with the lung a usually affected organ; in addition, the presence of anti-citrullinated protein antibodies (ACPA) is a common feature, which is caused by protein citrullination modifications, catalyzed by the peptidyl arginine deiminases (PAD) enzymes. We aimed to identify single nucleotide variants (SNV) in PADI2 and PADI4...

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Identifiers

PMID: 37759458
DOI: 10.3390/cells12182235
PMCID: PMC10527441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Molecular Factors in PAD2 (PADI2) and PAD4 (PADI4) Are Associated with Interstitial Lung Disease Susceptibility in Rheumatoid Arthritis Patients.PMID 37759458Read ↗

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