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Article

DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A2 in human vulnerable atherosclerotic plaque.

Clinical epigenetics - 21 Aug 2021

Li Jingjin, Zhang Xiaoping, Yang Mengxi, Yang Hang, Xu Ning, Fan Xueqiang, Liu Gang, Jiang Xintong, Fan Jiasai, Zhang Lifang, Zhang Hu, Zhou Ying, Li Rui, Gao Si, Jin Jiangli, Jin Zening, Zheng Jingang, Tu Qiang, Ren Jingyi

Abstract excerpt

BACKGROUND: Atherosclerotic plaque vulnerability is a key feature of atheroprogression and precipitating acute cardiovascular events. Although the pivotal role of epigenetic regulation in atherosclerotic plaque destabilization is being recognized, the DNA methylation profile and its potential role in driving the progression and destabilization of atherosclerotic cardiovascular disease remains largely unknown. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34419168
DOI: 10.1186/s13148-021-01152-z
PMCID: PMC8379831

Genes

PLA2G7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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