Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue factor pathway inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques.

Atherosclerosis - 1 Jun 2009

Zawadzki Christophe, Chatelain Nicolas, Delestre Marianne, Susen Sophie, Quesnel Bruno, Juthier Francis, Jeanpierre Emmanuelle, Azzaoui Richard, Corseaux Delphine, Breyne Joke, Torpier Gérard, Staels Bart, Van Belle Eric, Jude Brigitte

Abstract excerpt

BACKGROUND: The tissue factor pathway inhibitor-2 (TFPI-2) is a Kunitz-type serine-protease inhibitor which is expressed in atherosclerotic plaques. Epigenetic regulation of the TFPI-2 gene, through methylation of CpG islands, has been advocated in cancer. We hypothesized that TFPI-2 gene methyla...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carotid Arteries
Share to Carotid Artery Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CpG Islands

Share to DNA Methylation

Share to Down-Regulation

Share to Glycoproteins

Share to Promoter Regions, Genetic

Share to RNA, Messenger

Source

Identifiers

PMID: 19081094
DOI: 10.1016/j.atherosclerosis.2008.10.009

Genes

TFPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19081094-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue factor pathway inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques.PMID 19081094Read ↗

DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A2 in human vulnerable atherosclerotic plaque.Semantic proximity Read ↗

DNA methylation abnormalities in atherosclerosisSemantic proximity Read ↗

Integrated investigation of DNA methylation, gene expression and immune cell population revealed immune cell infiltration associated with atherosclerotic plaque formationSemantic proximity Read ↗

DNA methylation dynamics in human carotid plaques after cerebrovascular events.Semantic proximity Read ↗

Extensive demethylation of normally hypermethylated CpG islands occurs in human atherosclerotic arteries.Semantic proximity Read ↗

Tissue factor pathway inhibitor-2 was repressed by CpG hypermethylation through inhibition of KLF6 binding in highly invasive breast cancer cellsSemantic proximity Read ↗

Hypermethylation of TFPI2 correlates with cervical cancer incidence in the Uygur and Han populations of Xinjiang, China.Semantic proximity Read ↗

Methylation in the matrix metalloproteinase-2 gene is associated with cerebral ischemic stroke.Semantic proximity Read ↗

Synergistic Expression of Histone Deacetylase 9 and Matrix Metalloproteinase 12 in M4 Macrophages in Advanced Carotid Plaques.Semantic proximity Read ↗

Matrix metalloproteinase-1 promoter genotypes and haplotypes are associated with carotid plaque presence.Semantic proximity Read ↗

Cyclo-oxygenase-2 -765G > C promoter variants are associated with lower carotid plaque echogenicity in Japanese.Semantic proximity Read ↗

Elevated tissue expression of thrombomodulatory factors correlates with acute symptomatic carotid plaque phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.