Article
Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients.
Gene - 10 May 2014
Sharma Priyanka, Garg Gaurav, Kumar Arun, Mohammad Farhan, Kumar Sudha Ramesh, Tanwar Vinay Singh, Sati Satish, Sharma Abhay, Karthikeyan Ganesan, Brahmachari Vani, Sengupta Shantanu
Abstract excerpt
BACKGROUND: The alteration in the epigenome forms an interface between the genotype and the environment. Epigenetic alteration is expected to make a significant contribution to the development of cardiovascular disease where environmental interactions play a key role in disease progression. We had previously shown that global DNA hypermethylation per se is associated with coronary artery disease (CAD) and is...
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