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Article

Extensive demethylation of normally hypermethylated CpG islands occurs in human atherosclerotic arteries.

International journal of molecular medicine - 1 Nov 2010

Castillo-Díaz Silvia A, Garay-Sevilla María E, Hernández-González Martha A, Solís-Martínez Martha O, Zaina Silvio

Abstract excerpt

Global DNA hypomethylation potentially leading to pro-atherogenic gene expression occurs in atherosclerotic lesions. However, limited information is available on the genomic location of hypomethylated sequences. We present a microarray-based survey of the methylation status of CpG islands (CGIs)...

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Source

Identifiers

PMID: 20878091
DOI: 10.3892/ijmm_00000515

Genes

FOXP1
NOTCH1
PROX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20878091-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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