Article
Oral Juvenile Xanthogranuloma: A Clinicopathological, Immunohistochemical and BRAF V600E Study of Five New Cases, with Literature Review.
Head and neck pathology - 1 Jun 2022
Mota Carolina Peres, Silva Cunha John Lennon, Magalhães Maria Carolina Silva Versieux, Israel Mônica Simões, Freire Nathália de Almeida, Dos Santos Emilia Rosaria Carvalho, Canedo Nathalie Henriques Silva, Agostini Michelle, Abrahão Aline Corrêa, de Andrade Bruno Augusto Benevenuto, Romañach Mário José, de Sousa Sílvia Ferreira
Abstract excerpt
Juvenile xanthogranuloma (JXG) is the most common form of non-Langerhans cell histiocytosis and oral mucosal involvement is exceedingly rare. Histiocytic disorders harbor activating mutations in MAPK pathway, including the report of BRAF V600E in JXG of extracutaneous site. However, no information is available for oral JXG. Herein, the clinicopathological and immunohistochemical features of five new oral JXG were...
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