Oral Juvenile Xanthogranuloma: A Clinicopathological, Immunohistochemical and BRAF V600E Study of Five New Cases, with Literature Review.

doi:10.1007/s12105-021-01373-x

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Article

Oral Juvenile Xanthogranuloma: A Clinicopathological, Immunohistochemical and BRAF V600E Study of Five New Cases, with Literature Review.

Head and neck pathology - 1 Jun 2022

Mota Carolina Peres, Silva Cunha John Lennon, Magalhães Maria Carolina Silva Versieux, Israel Mônica Simões, Freire Nathália de Almeida, Dos Santos Emilia Rosaria Carvalho, Canedo Nathalie Henriques Silva, Agostini Michelle, Abrahão Aline Corrêa, de Andrade Bruno Augusto Benevenuto, Romañach Mário José, de Sousa Sílvia Ferreira

Abstract excerpt

Juvenile xanthogranuloma (JXG) is the most common form of non-Langerhans cell histiocytosis and oral mucosal involvement is exceedingly rare. Histiocytic disorders harbor activating mutations in MAPK pathway, including the report of BRAF V600E in JXG of extracutaneous site. However, no informatio...

Topics

Adolescent
Adult
Aged
Brazil
Female
Humans
Male
Middle Aged
Mutation
Proto-Oncogene Proteins B-raf
Xanthogranuloma, Juvenile
Young Adult

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Identifiers

PMID: 34414559
DOI: 10.1007/s12105-021-01373-x
PMCID: PMC9187812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-34414559-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.