Article
BRAF V600E mutation in pediatric intracranial and cranial juvenile xanthogranuloma.
Human pathology - 1 Nov 2017
Techavichit Piti, Sosothikul Darintr, Chaichana Thiamjit, Teerapakpinyo Chinachote, Thorner Paul Scott, Shuangshoti Shanop
Abstract excerpt
Juvenile xanthogranuloma (JXG) is a cutaneous form of non-Langerhans cell histiocytosis, primarily affecting children. The lesion is presumed to originate from either macrophages or dermal dendritic cells. JXG can rarely present as an isolated intracranial lesion and, in contrast to the dismal outcome of patients with systemic disease, cranial JXG has been shown to carry a more favorable prognosis. Here, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.