Article
Genetic evaluation of juvenile xanthogranuloma: genomic abnormalities are uncommon in solitary lesions, advanced cases may show more complexity.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2017
Paxton Christian N, O'Malley Dennis P, Bellizzi Andrew M, Alkapalan Deema, Fedoriw Yuri, Hornick Jason L, Perkins Sherrie L, South Sarah T, Andersen Erica F
Abstract excerpt
Juvenile xanthogranuloma is a rare histiocytic proliferation primarily affecting infants and young children, characterized by aberrant infiltration of histiocyte-derived cells in the skin, soft tissues and more rarely, visceral organs. Juvenile xanthogranuloma is generally considered to be a benign disorder; most lesions are solitary cutaneous nodules that resolve spontaneously without treatment. However, cases...
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