Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Validation of a multi-gene qPCR-based pharmacogenomics panel across major ethnic groups in Singapore and Indonesia.

Pharmacogenomics - 1 Nov 2021

Kothary Anar Sanjaykumar, Mahendra Caroline, Tan Mingchen, Min Tan Eunice Jia, Hong Yi Jacelyn Phua, Gabriella, Hui Jocelyn Tan Xin, Haruman Jessline Stephanie, Tan Zhihao, Lee Chun Kiat, Lezhava Alexander, Yan Benedict, Irwanto Astrid

Abstract excerpt

Aim: The clinical utility of pharmacogenomics (PGx) has been gaining traction alongside growing evidence that adverse drug reactions (ADRs) have significant genetic associations. Nala PGx Core® is a multi-gene qPCR-based panel of 20 allele variants, comprising 18 SNPs and two CYP2D6 copy number markers across four pharmacogenes - CYP2C9, CYP2C19, CYP2D6 and SLCO1B1. Methods: In this study, we validated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Benchmarking
Share to Cytochrome P-450 CYP2C19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Drug-Related Side Effects and Adverse Reactions

Share to Gene Dosage

Share to Indonesia

Share to Pharmacogenetics

Share to Singapore

Source

Identifiers

PMID: 34693729
DOI: 10.2217/pgs-2021-0071

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Validation of a multi-gene qPCR-based pharmacogenomics panel across major ethnic groups in Singapore and Indonesia.PMID 34693729Read ↗

Validation of a multi-gene qPCR-based pharmacogenomics panel across major ethnic groups in Singapore and IndonesiaSemantic proximity Read ↗

Analysis of Genetic Variation in CYP450 Genes for Clinical Implementation.Semantic proximity Read ↗

The variation landscape of CYP2D6 in a multi-ethnic Asian population.Semantic proximity Read ↗

The variation landscape of <i>CYP2D6</i> in a multi-ethnic Asian populationSemantic proximity Read ↗

Recommendations for Clinical CYP2D6 Genotyping Allele Selection: A Joint Consensus Recommendation of the Association for Molecular Pathology, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, and the European Society for Pharmacogenomics and Personalized Therapy.Semantic proximity Read ↗

Pharmacogenetics of common SNP affecting drug metabolizing enzymes: comparison of allele frequencies between European and Malaysian/Singaporean.Semantic proximity Read ↗

CYP3A4 and CYP3A5 Genotyping Recommendations: A Joint Consensus Recommendation of the Association for Molecular Pathology, Clinical Pharmacogenetics Implementation Consortium, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, European Society for Pharmacogenomics and Personalized Therapy, and Pharmacogenomics Knowledgebase.Semantic proximity Read ↗

Analytical and Clinical Validation of Action PharmaKitDx: A Comprehensive NGS Panel for the Identification of Pharmacogenetic Variants in Diverse PopulationsSemantic proximity Read ↗

Allele, Diplotype, and Phenotype Frequency Distribution of CYP2B6, CYP2C19, and CYP2D6 in the Han Population in North China.Semantic proximity Read ↗

Comparison of genome sequencing and clinical genotyping for pharmacogenesSemantic proximity Read ↗

Development of an Ancestrally Inclusive Preemptive Pharmacogenetic Testing Panel.Semantic proximity Read ↗

A Review of the Important Role of CYP2D6 in Pharmacogenomics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.