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Article

Overexpression of neuroserpin in larval and adult zebrafish shows different behavioral phenotypes.

Neuroscience letters - 25 Sept 2021

Han Sha, Zhang Dongyang, Dong Qiang, Wang Xu, Wang Liang

Abstract excerpt

Serpini1, which encodes neuroserpin, has been implicated in the development and maintenance of the nervous system. In this study, an inducible neuroserpin overexpression transgenic zebrafish was generated to investigate its role in different developmental stages. Neuroserpin overexpression was induced by doxycycline in larval and adult zebrafish respectively. Locomotion and thigmotaxis were recorded and analyzed...

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Identifiers

PMID: 34400286
DOI: 10.1016/j.neulet.2021.136175

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